Advanced Biotech Periodontal Plus AB - 4x25 mg

Advanced Biotech Products 77 First Cross Street Ragavan Colony Ashok Nagar Chennai Tamil Nadu 600083

• Formulation: Tetracycline Hydrochloride (25 mg) in Type-I collagen fibrils

• Packaging: Available in boxes of 4 vials, each containing 25 mg

• Sterilization method: Ethylene oxide gas

• Storage conditions: Store at ambient temperature (4°C to 40°C / 39°F to 104°F)

Preparation:

• Use aseptic technique to open the packaging.

• Dispense the required quantity of PPAB into a clean dappen dish.

• Moisten the material with a drop of sterile distilled water to activate it.

 Application:

• Using a sterile tweezer, pick up the hydrated material.

• Place the material near the periodontal pocket margins.

• Insert the PPAB into the pocket using a composite handling instrument or a blunt-ended periodontal probe.

• Close the site if necessary and proceed with post-operative care as per standard clinical guidelines.

Post-Application Guidelines:

• Ensure the patient avoids dislodging the material by following soft diet instructions and avoiding vigorous rinsing for the first 24 hours.

• Re-application, if needed, can be done after clinical evaluation.

Important Handling Instructions:

• PPAB is single-use only. Do not resterilize or reuse.

• Once the package is opened, any unused material must be discarded immediately.

Caution:

• This product is intended for use only by registered dental practitioners.

• Available by medical prescription only.

• Use with caution in individuals with a history of allergy, asthma, high fever, or urticaria, as sensitivity reactions may occur.

• Store at ambient temperature (4°C to 40°C / 39°F to 104°F).

Periodontal Plus AB (PPAB) is indicated for use as a local drug delivery agent in the treatment and management of periodontal diseases. It is specifically recommended for:

• Chronic and aggressive periodontitis

• Persistent pocket infections unresponsive to mechanical debridement alone

• Localized periodontal lesions requiring adjunctive antimicrobial therapy

• As a supportive treatment in non-surgical and surgical periodontal procedures

• Cases where targeted, sustained release of tetracycline is beneficial for controlling infection and promoting healing

• Sustained Drug Release:
  PPAB delivers a controlled and consistent release of Tetracycline from day one, maintaining therapeutic levels for 10 to 14 days, with peak concentrations typically reached around the 4th to 5th day.

• Dual Mechanism of Action:
  Combines the antimicrobial action of Tetracycline with the bioregenerative support of high-purity Type-I collagen fibrils, which gradually biodegrade and release enzymes that aid in periodontal tissue repair.

• Effective Inflammation Control:
  Clinical studies and practitioner feedback report significant reduction in inflammation, bleeding, and exudation—often within just two applications.

• Minimally Invasive, Highly Acceptable:
  The easy and minimally invasive application of PPAB promotes greater patient acceptance, particularly when preparing for more advanced phases of periodontal treatment, if required.

• Clinically Proven Outcomes:
  Periodontists using PPAB have consistently observed rapid clinical resolution, improved healing outcomes, and enhanced tissue health, making it a reliable adjunct in periodontal therapy.